Manufactured insulin can be either synthetic (human) or animal in origin, and falls into five main categories
- rapid-acting
- short-acting
- intermediate acting (also called isophane insulin)
- fixed mixtures (of rapid - or short-acting and intermediate-acting insulin)
- long-acting
Indications for insulin treatment
Strong indications for insulin therapy include:
- symptoms of hyperglycaemia such as polyuria, thirst,recurrent fungal infections (especially genital thrush) or bacterial infections (especially urine infections
- pregnancy or planning pregnancy
- oral hypoglycaemic treatments not tolerated/ contra-indicated
- weight loss without dieting in someone of low or normal weight.
Possible indications for insulin therapy include:
- unsatisfactory glycaemic control, even with the maximum tolerated dose of oral hypoglycaemic agents (OHAs) (HbA1c higher than 7 per cent, self blood glucose monitoring results higher than 7 mmols/litre before meals or 9 mmols/litre two hours after meals)
- personal preference
- painful neuropathy
- foot ulceration and infection.
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